Follicular lymphoma (follicular lymphoma) Follicular lymphoma is an indolent B-cell tumor derived from cells in the germinal center of lymphoid follicles. It accounts for about 25% to 45% of the NHL in European and American countries or regions

Non-Hodgkin's lymphoma (NHL) accounts for about 80% to 90% of all lymphomas, of which two-thirds are primary in the lymph nodes, and one-third are primary in organs or tissues outside the lymph nodes, such as Digestive and respiratory tract, lungs, skin, salivary glands, thyroid and central nervous system, etc.

The tumor cells of Burkitt's lymphoma are relatively mature B cells, which express monoclonal cell membrane surface immunoglobulins such as sIg, CD19, CD20 and CD10. All Burkitt lymphomas have translocations related to the c-myc gene on chromosome 8. The most common is t(8;14), and t(2;8) or t(8;22) can also occur.

Pre-B-cell ALL/LBL patients are mainly children under 10 years of age, with extensive bone marrow involvement, swelling of the liver, spleen, and lymph nodes, as well as abnormal cells in the peripheral blood. Patients with pre-T-cell ALL are mostly adolescents

NHL examinations can be divided into traumatic and non-traumatic examinations. Traumatic examinations are mostly carried out by taking histological specimens for diagnosis, while non-invasive examinations are mostly carried out for finding the location of the lesion, evaluating the extent of the lesion and evaluating the therapeutic effect.

The application of modern radiotherapy and chemotherapy has made Hodgkin’s lymphoma a curable tumor, but follow-up results of a large number of long-term surviving patients show that the 15-year mortality rate is 31% higher than that of the general population

Classical HL (classical Hodgkin's lymphoma, CHL) Classical HL is composed of small lymphocytes, eosinophils, neutrophils, histiocytes, plasma cells, fibroblasts and collagen fibers scattered in various non-tumorous cells